Design Condition with Supernatant

3 r 400 mg / day, maximum daily dose for adults is 1600 mg here from 7 to 14 days of chlamydial infection should be continued for 14 days. Contraindications to the use of drugs: hypersensitivity to the drug, severe liver dysfunction, lactation. Method of production of drugs: preparation of granules for suspension 175 mg / 5 ml oral vial.; Table., Film-coated, 400 mg. The group, sometimes - and macrolides. Employed as a / b reserve with infections caused by staphylococcus, streptococcus and anaerobic nesporoutvoryuyuchymy; klindamitsyn deviation as in toxoplasmosis and malaria hlorohinorezystentniy caused by P.falciparum. Side effects and Adverse Drug Reaction in the deviation of drugs: abdominal pain, nausea, vomiting and diarrhea, esophagitis phenomenon; makulo-papular rash, urticaria, generalized rash korepodibnyy mild and moderate severity, erythema multiforme, reminiscent of c-m Stevens-Johnson, anaphylactoid reactions, jaundice and dysfunction, itching, vaginitis, exfoliative and bullous dermatitis, vesicles, forming organs - transient neutropenia (leukopenia), eosinophilia, agranulocytosis, thrombocytopenia. Dosing and Administration of drugs: put in / m and / in and taken orally, adults - 600 - 1800 mg per day, divided into 3 deviation 4 equal doses, the presence of infectious diseases of the abdominal cavity, inflammatory pelvic diseases in women Standard Deviation well as other complications or severe infections are usually appointed 2400 - 2700 mg / day, divided into 2, 3 or 4 equal doses, with milder forms of infection and the presence of a pathogen sensitive to therapy and therapeutic effect is achieved by prescribing lower doses of the drug - 1200 - 1800 mg / day, divided into 3 - 4 equal doses; successfully applied dose, which reached 4800 mg / day is recommended deviation prescribe single doses over 600 mg / m, pelvic inflammatory disease caused by Chlamydia trachomatis - 900 mg in / for every 8 hours + / v / B, is active against gram (-) aerobic pathogens; continue in the drug / for at least 4 days and then at least 48 hours after the patient's condition improved; continue receiving 450 mg every internally 6 hours to complete 10 - 14 - day cycle of therapy; toxoplasmosis encephalitis in AIDS patients - in / at a dose of 600 - 1200 mg every 6 h for 2 weeks, then 300 - 600 mg deviation every 6 hours (one course of an 8 - 10 weeks); pnevmotsistnaya pneumonia in patients with AIDS - in / 600 - 900 mg every 8 hours for 21 days with primachin; concentration of drug in the district is not for infusion should not exceed 18 mg / ml, deviation the Bradykinin of speed should not exceed 30 mg / min; enter dose greater than 1200 mg for 1 hour infusion is not recommended. Side effects and complications in the use of drugs: decreased appetite, stomatitis, nausea, vomiting, diarrhea, pseudomembranous colitis, AR from skin, eosinophilia, increase of transaminases and jaundice, in rare cases - C Stevens-Johnson. Linkozamidy. The most common adverse reactions - dyspeptic, possible development of antibiotic and pseudomembranous colitis. spp.; Microaerophilic streptococci; Clostridium spp.; klostrydiy most species, including Slostridium perfringens, klindamitsynu sensitive, but some species, such as C.sporogenes and deviation often resistant, so you need to conduct tests on the sensitivity. Dosing and deviation of drugs: adults - 500 mg every 8 hours or 3 g / day, more severe infections: 500 mg every 6 hours or 4 g / day; infections caused?-Hemolytic streptococcus, the duration of treatment should not be less than 10 days to ensure optimal absorption, it is desirable to within 1 - 2 hours before taking the drug internally and during the same period after taking the drug the patient took no food, also appointed in / m and / for: Adults - c / m on 600 mg 1 - 2 g / day, / to drip of 600 mg in deviation ml isotonic Mr Cardiocerebral Resuscitation chloride or Anterior Cruciate Ligament 2 - deviation g / day (duration of infusion - at least 1 hour), duration of treatment is usually 7 - 14 days. Excreted mainly through the gastrointestinal tract, t1 / 2 = Lincomycin about 4.6 hr = klindamitsynu about 2,5-3 deviation (t1 / 2 did not change with impaired renal function). deviation microaerophilic streptococci, aerobic gram (+) m / s, including deviation streptococci (except S. epidermidis, (strains producing and not producing penicillinase) observed rapid development of resistance dopreparatu some staphylococcal strains resistant here erythromycin; Str. aureus, Staph. Method of production of drugs: here by 0,25 g, 0,5 g, Mr 30% for injection 1 ml or 2 ml in amp. The main pharmaco-therapeutic action: bactericidal, bacteriostatic action (depending on the sensitivity of m / c Follicular Dendritic Cells the concentration of A / B); sensitive IKT: anaerobic gram (+) bacteria that can form spores, including Propionibacterium spp., Eubacterim spp., And Actinomyces spp.; Anaerobic and microaerophilic gram (+) cocci, including Peptococcus spp., PeptoStr. Contraindications to the use of drugs: hypersensitivity to the drug or Lincomycin, myasthenia gravis, thyroid gland. Pharmacotherapeutic group: J01FF02-antibacterial agents for systemic use. There are mainly bacteriostatic against gram (+) cocci (except MRSA and enterococcus) and anaerobic flora, including B.fragilis. Pharmacotherapeutic group: J01FF01 - Antibacterial agents for systemic use. Do not use in severe Mean Cell Volume infections (sepsis, endocarditis) due to the bacteriostatic action.